Journal of the Formosan Medical Association
Volume 106, Issue 7 , Pages 520-527 , 2007

Laboratory Investigation of a Nosocomial Transmission of Tuberculosis at a District General Hospital

  • Wei-Lun Huang

      Affiliations

    • Reference Laboratory of Mycobacteriology, Research and Diagnostic Center, Centers for Disease Control, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan
    • ,
  • Ruwen Jou

      Affiliations

    • Reference Laboratory of Mycobacteriology, Research and Diagnostic Center, Centers for Disease Control, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Ruwen Jou, Reference Laboratory of Mycobacteriology, Research and Diagnostic Center, Centers for Disease Control, Department of Health, 161 Kun-Yang Street, Nan-Kang, Taipei 115, Taiwan
    • ,
  • Pen-Fang Yeh

      Affiliations

    • Department of Health, and Department of Internal Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan
    • ,
  • Angela Huang

      Affiliations

    • Department of Health, and Department of Internal Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan
    • ,
  • the Outbreak Investigation Team

Received 21 September 2006 ,Revised 29 March 2007 ,Accepted 10 April 2007.

References 

  1. Phillips MS , von Reyn CF . Nosocomial infections due to nontuberculous mycobacteria . Clin Infect Dis . 2001;33:1363–1374
  2. Greenaway C , Menzies D , Fanning A , et al.   Delay in diagnosis among hospitalized patients with active tuberculosis–predictors and outcomes . Am J Respir Crit Care Med . 2002;165:927–933
  3. Wilkins D , Woolcock AJ , Cossart YE . Tuberculosis: medical students at risk . Med J Aust . 1994;160:395–397
  4. Yologlu S , Durmaz B , Bayindir Y . Nosocomial infections and risk factors in intensive care units . New Microbiol . 2003;26:299–303
  5. Larson JL , Lambert L , Stricof RL , et al.   Potential nosocomial exposure to Mycobacterium tuberculosis from a broncho-scope . Infect Control Hosp Epidemiol . 2003;24:825–830
  6. Conde MB , Loivos AC , Rezende VM , et al.   Yield of sputum induction in the diagnosis of pleural tuberculosis . Am J Respir Crit Care Med . 2003;167:723–725
  7. McWilliams T , Wells AU , Harrison AC , et al.   Induced sputum and bronchoscopy in the diagnosis of pulmonary tuberculosis . Thorax . 2002;57:1010–1014
  8. Keijman J , Tjhie J , Olde DS , et al.   Unusual nosocomial transmission of Mycobacterium tuberculosis . Eur J Clin Microbiol Infect Dis . 2001;20:808–809
  9. Merlani GM , Francioli P . Established and emerging water-borne nosocomial infections . Curr Opin Infect Dis . 2003;16:343–347
  10. Wan GH , Lu SC , Tsai YH . Polymerase chain reaction used for the detection of airborne Mycobacterium tuberculosis in health care settings . Am J Infect Control . 2004;32:17–22
  11. Menzies D , Fanning A , Yuan L , et al.   Tuberculosis among health care workers . N Engl J Med . 1995;332:92–98
  12. Nosocomial transmission of Mycobacterium tuberculosis found through screening for severe acute respiratory syndrome–Taipei, Taiwan, 2003 . MMWR . 2004;53:321–322
  13. Chen YC , Chen PJ , Chang SC , et al.   Infection control and SARS transmission among healthcare workers, Taiwan . Emerg Infect Dis . 2004;10:895–898
  14. Chen ZC. Tuberculosis Annual Report, 2002. Taipei: Center for Disease Control, Department of Health, Taiwan.
  15. Veen J . Microepidemics of tuberculosis: the stone-in-the-pond principle . Tuber Lung Dis . 1992;73:73–76
  16. Rastogi N , Goh KS , David HL . Drug susceptibility testing in tuberculosis: a comparison of the proportion methods using Lowenstein-Jensen, Middlebrook 7H10 and 7H11 agar media and a radiometric method . Res Microbiol . 1989;140:405–417
  17. Telenti A , Imboden P , Marchesi F , et al.   Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis . Lancet . 1993;341:647–650
  18. Rad ME , Bifani P , Martin C , et al.   Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family . Emerg Infect Dis . 2003;9:838–845
  19. van Embden JD , Cave MD , Crawford JT , et al.   Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology . J Clin Microbiol . 1993;31:406–409
  20. Kamerbeek J , Schouls L , Kolk A , et al.   Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology . J Clin Microbiol . 1997;35:907–914
  21. Chin PJ , Jou R . A modified automated high-throughput mycobacterial interspersed repetitive unit method for genotyping Mycobacterium tuberculosis . Diagn Microbiol Infect Dis . 2005;53:325–327
  22. Narvskaya O , Otten T , Limeschenko E , et al.   Nosocomial outbreak of multidrug-resistant tuberculosis caused by a strain of Mycobacterium tuberculosis W-Beijing family in St. Petersburg, Russia . Eur J Clin Microbiol Infect Dis . 2002;21:596–602
  23. Jou R , Chiang CY , Huang WL . Distribution of the Beijing family genotypes of Mycobacterium tuberculosis in Taiwan . J Clin Microbiol . 2005;43:95–100
  24. Bifani PJ , Mathema B , Liu Z , et al.   Identification of a W variant outbreak of Mycobacterium tuberculosis via population-based molecular epidemiology . JAMA . 1999;282:2321–2327
  25. Supply P , Lesjean S , Savine E , et al.   Automated high-throughput genotyping for study of global epidemiology of Mycobacterium tuberculosis based on mycobacterial interspersed repetitive units . J Clin Microbiol . 2001;39:3563–3571
  26. Qian L , Van Embden JD , Van Der Zanden AG , et al.   Retrospective analysis of the Beijing family of Mycobacterium tuberculosis in preserved lung tissues . J Clin Microbiol . 1999;37:471–474
  27. Kent JH . The epidemiology of multidrug-resistant tuberculosis in the United States . Med Clin North Am . 1993;77:1391–1409

PII: S0929-6646(07)60002-3

doi: 10.1016/S0929-6646(07)60002-3

Journal of the Formosan Medical Association
Volume 106, Issue 7 , Pages 520-527 , 2007

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