Journal of the Formosan Medical Association
Volume 107, Issue 10 , Pages 791-797 , October 2008

Clinical Characteristics of Nosocomial Rotavirus Infection in Children in Taiwan

  • Jian-Te Lee

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Chun-Nan Lee

      Affiliations

    • Department of Laboratory Medicine, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Pei-Lan Shao

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Luan-Yin Chang

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Chun-Yi Lu

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Ping-Ing Lee

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Chun-Min Chen

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Chin-Yun Lee

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Li-Min Huang

      Affiliations

    • Department of Pediatrics, Yunlin Branch, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Li-Min Huang, Department of Pediatrics, National Taiwan University Hospital, 7/F, 7 Chung-Shan South Road, Taipei 100, Taiwan

Received 20 August 2007 ,Revised 14 November 2007 ,Accepted 13 May 2008.

References 

  1. Bishop RF , Davidson GP , Holmes IH , et al.   Virus particles in epithelial cells of duodenal mucosa from children with acute nonbacterial gastroenteritis . Lancet . 1973;2:1281–1283
  2. Rodriguez WJ , Kim HW , Arrobio JO , et al.   Clinical features of acute gastroenteritis associated with human reovirus-like agent in infants and young children . J Pediatr . 1977;91:188–193
  3. Bresee JS , Hummelman E , Nelson EA , et al.   Rotavirus in Asia: the value of surveillance for informing decisions about the introduction of new vaccines . J Infect Dis . 2005;192:S1–S5
  4. Parashar UD , Gibson CJ , Bresse JS , et al.   Rotavirus and severe childhood diarrhea . Emerg Infect Dis . 2006;12:304–306
  5. Chen KT , Chen PY , Tang RB , et al.   Sentinel hospital surveillance for rotavirus diarrhea in Taiwan, 2001–2003 . J Infect Dis . 2005;192:S44–S48
  6. Fischer TK , Bresee JS , Glass RI . Rotavirus vaccines and the prevention of hospital-acquired diarrhea in children . Vaccine . 2004;22(Suppl 1):S49–S54
  7. Lam BC , Tam J , Ng MH , et al.   Nosocomial gastroenteritis in paediatric patients . J Hosp Infect . 1989;14:351–355
  8. Chen HN , Dennehy PH , Oh W , et al.   Outbreak and control of a rotaviral infection in a nursery . J Formos Med Assoc . 1997;96:884–889
  9. Gentsch JR , Glass RI , Woods P , et al.   Identification of group A rotavirus gene 4 types by polymerase chain reaction . J Clin Microbiol . 1992;30:1365–1373
  10. Lee CN , Lin CC , Kao CL , et al.   Genetic characterization of the rotaviruses associated with a nursery outbreak . J Med Virol . 2001;63:311–320
  11. Saulsbury FT , Winkelstein JA , Yolken RH . Chronic rotavirus infection in immunodeficiency . J Pediatr . 1980;97:61–65
  12. Fitts SW , Green M , Reyes J , et al.   Clinical features of nosocomial rotavirus infection in pediatric liver transplant recipients . Clin Transplant . 1995;9:201–204
  13. Christie IL , Totterdell BM , Banatvala JE . False positive rotazyme tests on faecal samples from babies . Lancet . 1983;2:1028
  14. Cone R , Mohan K , Thouless M , et al.   Nosocomial transmission of rotavirus infection . Pediatr Infect Dis J . 1988;7:103–109
  15. Gleizes O , Desselberger U , Tatochenko V , et al.   Nosocomial rotavirus infection in European countries. A review of the epidemiology, severity and economic burden of hospital-acquired rotavirus disease . Pediatr Infect Dis J . 2006;25:S12–S21
  16. Raphael RA , Sattar SA , Springthorpe VS . Long-term survival of human rotavirus in raw and treated river water . Can J Microbiol . 1985;31:124–128
  17. Centers for Disease Control and Prevention  . Guideline for hand hygiene in health-care settings: recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force . Morb Mortal Wkly Rep . 2002;51(RR-16):8–16
  18. Ward RL , Bernstein DI , Young EC , et al.   Human rotavirus studies in volunteers: determination of infectious dose and serological response to infection . J Infect Dis . 1986;154:871–880
  19. Satter SA , Lloyd-Evans N , Springthorpe VS , et al.   Institutional outbreaks of rotavirus diarrhea: potential role of fomites and environmental surfaces as vehicles for virus transmission . J Hyg . 1986;96:277–289
  20. Dennehy PH , Peter G . Risk factors associated with nosocomial rotavirus infection . Am J Dis Child . 1985;139:935–939
  21. Widdowson MA , van Doornum GJ , van der Poel WH , et al.   An outbreak of diarrhea in a neonatal medium care unit caused by a novel strain of rotavirus: investigation using both epidemiologic and microbiological methods . Infect Control Hosp Epidemiol . 2002;23:665–670
  22. Gianino P , Mastretta E , Longo P , et al.   Incidence of nosocomial rotavirus infections, symptomatic and asymptomatic, in breast-fed and non-breast-fed infants . J Hosp Infect . 2002;50:13–17
  23. Mastretta E , Longo P , Laccisaglia A , et al.   Effect of Lactobacillus GG and breast-feeding in the prevention of rotavirus nosocomial infection . J Pediatr Gastroenterol Nutr . 2002;35:527–531
  24. Barnes GL , Callaghan SL , Kirkwood CD , et al.   Excretion of serotype G1 rotavirus strains by asymptomatic staff: a possible source of nosocomial infection . J Pediatr . 2003;142:722–725
  25. American Academy of Pediatrics  . Children in out-of-home child care . In:  Pickering LK ,  Baker CJ ,  Long SS , et al. editor. Red Book: 2006 Report of the Committee on Infectious Diseases . 27th edition. Elk Grove Village, IL: American Academy of Pediatrics; 2006;p. 130–145
  26. Pickering L , Bartlett AI , Reves P , et al.   Asymptomatic excretion of rotavirus before and after rotavirus diarrhea in children in day care centers . J Pediatr . 1988;12:361–365
  27. Dennehy PH , Nelson SM , Crowley BA , et al.   Detection of rotavirus RNA in hospital air samples by polymerase chain reaction (PCR) . Pediatr Res . 1998;43:143A
  28. Zerr DM , Allpress AL , Heath J , et al.   Decreasing hospital-associated rotavirus infection: a multidisciplinary hand hygiene campaign in a children's hospital . Pediatr Infect Dis J . 2005;24:397–403
  29. Szajewska H , Mrukowicz JZ . Use of probiotics in children with acute diarrhea . Pediatr Drugs . 2005;7:111–122
  30. Jusot JF , Vanhems P , Benzait F , et al.   Reported measures of hygiene and incidence rates for hospital-acquired diarrhea in 31 French pediatric wards: is there any relation-ship? . Infect Control Hosp Epidemiol . 2003;24:520–525
  31. Ruiz-Palacios GM , Perez-Schael I , Velazquez FR , et al.   Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis . N Engl J Med . 2006;354:11–22
  32. Vesikari T , Matson DO , Dennehy P , et al.   Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine . N Engl J Med . 2006;354:23–33
  33. Chen SY , Chang YC , Lee YS , et al.   Molecular epidemiology and clinical manifestations of viral gastroenteritis in hospitalized pediatric patients in northern Taiwan . J Clin Microbiol . 2007;45:2054–2057
  34. Foppa IM , Karmaus W , Ehlken B , et al.   Health care-associated rotavirus illness in pediatric inpatients in Germany, Austria, and Switzerland . Infect Control Hosp Epidemiol . 2006;27:633–635
  35. Piednoir E , Bessaci K , Bureau-Chalot F , et al.   Economic impact of healthcare-associated rotavirus infection in a paediatric hospital . J Hosp Infect . 2003;55:190–195
  36. Ratner AJ , Neu N , Jakob K , et al.   Nosocomial rotavirus in a pediatric hospital . Infect Control Hosp Epidemiol . 2001;22:299–301

PII: S0929-6646(08)60192-8

doi: 10.1016/S0929-6646(08)60192-8

Journal of the Formosan Medical Association
Volume 107, Issue 10 , Pages 791-797 , October 2008

Article Tools