Journal of the Formosan Medical Association
Volume 107, Issue 10 , Pages 816-821 , October 2008

Disease Progression in a Patient with Nonalcoholic Steatohepatitis

  • Ping-Huei Tseng

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Chun-Jen Liu

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Jia-Horng Kao

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Hepatitis Research Center, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Graduate Institute of Clinical Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Chia-Tung Shun

      Affiliations

    • Department of Forensic Medicine and Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Pei-Jer Chen

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Hepatitis Research Center, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Graduate Institute of Clinical Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Ding-Shinn Chen

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Hepatitis Research Center, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Graduate Institute of Clinical Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Ding-Shinn Chen, Hepatitis Research Center, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei 100, Taiwan

Received 9 May 2007 ,Revised 27 June 2007 ,Accepted 7 August 2007.

References 

  1. Matteoni CA , Younossi ZM , Gramlich T , et al.   Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity . Gastroenterology . 1999;116:1413–1419
  2. Ludwig J , Viaggiano TR , McGill DB , et al.   Nonalcoholic steatohepatitis: Mayo Clinic experience with an hitherto unnamed disease . Mayo Clin Proc . 1980;55:434–438
  3. Angulo P . Nonalcoholic fatty liver disease . N Engl J Med . 2002;16:1221–1231
  4. Bellentani S , Saccoccio G , Masatti F , et al.   Prevalence of and risk factors for hepatic steatosis in Northern Italy . Ann Intern Med . 2000;132:112–117
  5. Marchesini G , Bugianesi E , Forlani G , et al.   Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome . Hepatology . 2003;37:917–923
  6. Clark JM , Brancati FL , Diehl AM . Nonalcoholic fatty liver disease . Gastroenterology . 2002;122:1649–1657
  7. Neuschwander-Tetri BA , Caldwell SH . Nonalcoholic steato-hepatitis: summary of an AASLD single topic conference . Hepatology . 2003;37:1202–1219
  8. Brunt EM , Janney CG , Di Bisceglie AM , et al.   Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions . Am J Gastroenterol . 1999;94:2467–2474
  9. Marchesini G , Brizi M , Bianchi G , et al.   Nonalcoholic fatty liver disease: a feature of the metabolic syndrome . Diabetes . 2001;50:1844–1850
  10. Farrell GC , Larter CZ . Nonalcoholic fatty liver disease: from steatosis to cirrhosis . Hepatology . 2006;43:S99–112
  11. Pei D , Kuo SW , Wu DA , et al.   The relationships between insulin resistance and components of metabolic syndrome in Taiwanese Asians . Int J Clin Pract . 2005;59:1408–1416
  12. Saadeh S , Younossi ZM , Remer EM , et al.   The utility of radiological imaging in nonalcoholic fatty liver disease . Gastroenterology . 2002;123:745–750
  13. Yang PM , Hung GT , Lin JT , et al.   Ultrasonography in the diagnosis of benign diffuse parenchymal liver diseases: a prospective study . J Formos Med Assoc . 1988;87:966–977
  14. Dixon JB , Bhathal PS , Hughs NR , et al.   Nonalcoholic fatty liver disease: improvement in liver histological analysis with weight loss . Hepatology . 2004;39:1647–1654
  15. Day CP . Natural history of NAFLD: remarkably benign in the absence of cirrhosis . Gastroenterology . 2005;129:375–378
  16. Adams LA , Lymp JF , St Sauver J , et al.   The natural history of nonalcoholic fatty liver disease: a population-based cohort study . Gastroenterology . 2005;129:113–121
  17. Dam-Larsen S , Franzmann M , Andersen IB , et al.   Long term prognosis of fatty liver: risk of chronic liver disease and death . Gut . 2004;53:750–755
  18. Adams LA , Sanderson S , Lindor KD , et al.   The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies . J Hepatol . 2005;42:132–138
  19. Wong VW , Chan HL , Hui AY , et al.   Clinical and histological features of non-alcoholic fatty liver disease in Hong Kong Chinese . Aliment Pharmacol Ther . 2004;20:45–49
  20. Hui AY , Wong VW , Chan HL , et al.   Histological progression of non-alcoholic fatty liver disease in Chinese patients . Aliment Pharmacol Ther . 2005;21:407–413
  21. Lai SW , Tan CK , Ng KC . Epidemiology of fatty liver in a hospital-based study in Taiwan . South Med J . 2002;11:1288–1292
  22. Liew PL , Lee WJ , Lee YC , et al.   Hepatic histopathology of morbid obesity: concurrence of other forms of chronic liver disease . Obes Surg . 2006;16:1584–1593
  23. Liu CJ , Chen PJ , Jeng YM , et al.   Serum adiponectin correlates with viral characteristics but not histologic features in patients with chronic hepatitis C . J Hepatol . 2005;43:235–242
  24. Liu CJ , Jeng YM , Chen PJ , et al.   Influence of metabolic syndrome, viral genotype and antiviral therapy on super-imposed fatty liver disease in chronic hepatitis C . Antivir Ther . 2005;10:405–415

PII: S0929-6646(08)60196-5

doi: 10.1016/S0929-6646(08)60196-5

Journal of the Formosan Medical Association
Volume 107, Issue 10 , Pages 816-821 , October 2008