Journal of the Formosan Medical Association
Volume 105, Issue 7 , Pages 542-549 , 2006

Safety and Immunogenicity of Heptavalent Pneumococcal Conjugate Vaccine Booster in Taiwanese Toddlers

  • Chun-Yi Lu

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
  • ,
  • Luan-Yin Chang

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
  • ,
  • Fu-Yuan Huang

      Affiliations

    • Department of Pediatrics, Taipei Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Chin-Yun Lee

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
  • ,
  • Li-Min Huang

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Li-Min Huang, Department of Pediatrics, National Taiwan University Hospital, 7, Chung-Shan South Road, Taipei 100, Taiwan

Received 12 August 2005 ,Revised 21 November 2005 ,Accepted 6 December 2005.

References 

  1. Shao PL , Lu CY , Chang LY , et al.   Safety and immunogeni-city of heptavalent penumococcal conjugate vaccine in Taiwanese infants . J Formos Med Assoc . 2004;103:613–617
  2. Scheifele D , Halperin S , Pellertier L , et al.   Invasive pneu-mococcal infections in Canadian children, 1991–1998: implications for new vaccination strategies . Clin Infect Dis . 2000;31:58–64
  3. Kaplan SL , Mason EO , Barson WJ , et al.   Three-year multi-center surveillance of systemic pneumococcal infections in children . Pediatrics . 1998;102:538–545
  4. Recommendations of the Advisory Committee on Immunization Practices (ACIP)  . Preventing pneumococcal disease among infants and young children . MMWR . 2000;49(RR09):1–38
  5. Hsieh YC , Hsueh PR , Lu CY , et al.   Clinical manifestations and molecular epidemiology of necrotizing pneumonia and empyema caused by Streptococcus pneumoniae in children in Taiwan . Clin Infect Dis . 2004;38:830–835
  6. Black S , Shinefield H , Fireman B , et al.   Efficacy, safety, and immunogenicity of heptavalent pneumococcal conjugate vaccine in children . Pediatr Infect Dis J . 2000;19:187–195
  7. Eskola J , Kilpi T , Palmu A , et al.   Efficacy of a pneumococcal conjugate vaccine against acute otitis media . N Engl J Med. . 2001;344:403–409
  8. Shinefield HR , Black S , Ray P , et al.   Safety and immuno-genicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers . Pediatr Infect Dis J . 1999;18:757–763
  9. Rennels MB , Edwards KM , Keyserling HL , et al.   Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants . Pediatrics . 1998;101:604–611
  10. Jodar L , Butler J , Carlone G , et al.   Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants . Vaccine . 2003;21:3265–3272
  11. Quataert SA , Kirch CS , Wiedl LJ , et al.   Assignment of weight-based antibody units to a human antipneumococcal standard reference serum, lot 89-S . Clin Diagn Lab Immunol . 1995;2:590–597
  12. Tichmann-Schumann I , Soemantri P , Behre U , et al.   Immunogenicity and reactogenicity of four doses of diphtheria-tetanus-three-component acellular pertussis-hepatitis B-inactivated polio virus-Haemophilus influenzae type b vaccine coadministered with 7-valent pneumococcal conjugate vaccine . Pediatr Infect Dis J . 2005;24:70–77
  13. Jokinen JT , Ahman H , Kilpi TM , et al.   Concentration of antipneumococcal antibodies as a serological correlate of protection: an application to acute otitis media . J Infect Dis . 2004;190:545–550
  14. Goldblatt D . Conjugate vaccines . Clin Exp Immunol . 2000;119:1–3
  15. Makela PH , Kayhty H , Leino T , et al.   Long-term persistence of immunity after immunization with Haemophilus influen-zae type b conjugate vaccine . Vaccine . 2003;22:287–292
  16. Black SB , Shinefield HR , Hansen J , et al.   Postlicensure evaluation of the effectiveness of seven valent pneumococcal conjugate vaccine . Pediatr Infect Dis J . 2001;20:1105–1107
  17. Stephens DS , Zughaier SM , Whitney CG , et al.   Incidence of macrolide resistance in Streptococcus pneumoniae after introduction of the pneumococcal conjugate vaccine: population-based assessment . Lancet . 2005;365:855–863
  18. Talbot TR , Poehling KA , Hartert TV , et al.   Reduction in high rates of antibiotic-nonsusceptible invasive pneumococcal disease in Tennessee after introduction of the pneumococ-cal conjugate vaccine . Clin Infect Dis . 2004;39:641–648
  19. Lipstich M . Bacterial vaccines and serotype replacement: lessons from Haemophilus influenzae and prospects for Streptococcus pneumoniae . Emerg Infect Dis . 1999;5:336–345
  20. Veenhoven R , Bogaert D , Uiterwaal C , et al.   Effect of conjugate pneumococcal vaccine followed by polysaccharide pneumococcal vaccine on recurrent acute otitis media: a randomized study . Lancet . 2003;361:2189–2195
  21. Porat N , Arguedas A , Spratt BG , et al.   Emergence of penicillin-nonsusceptible Streptococcus pneumoniae clones expressing serotypes not present in the antipneumococcal conjugate vaccine . J Infect Dis . 2004;190:2154–2161
  22. Hsueh PR , Teng LJ , Lee LN , et al.   Extremely high incidence of macrolide and trimethoprim-sulfamethoxazole resistance among clinical isolates of Streptococcus pneumoniae in Taiwan . J Clin Microbiol . 1999;37:897–901
  23. Siu LK , Chu ML , Ho M , et al.   Epidemiology of invasive pneumococcal infection in Taiwan: antibiotic resistance, serogroup distribution, and ribotypes analyses . Microb Drug Resist . 2002;8:201–208

PII: S0929-6646(09)60148-0

doi: 10.1016/S0929-6646(09)60148-0

Journal of the Formosan Medical Association
Volume 105, Issue 7 , Pages 542-549 , 2006