Journal of the Formosan Medical Association
Volume 105, Issue 7 , Pages 577-582, 2006

Diffuse Intraperitoneal Metastasis After Spontaneous Rupture of Hepatocellular Carcinoma

  • Chien-Chu Lin

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan
    • ,
  • Chien-Hung Chen

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Chien-Hung Chen, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, 7, Chung-Shan South Road, Taipei 100, Taiwan
    • ,
  • Yuk-Ming Tsang

      Affiliations

    • Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • ,
  • I-Shiow Jan

      Affiliations

    • Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • ,
  • Jin-Chuan Sheu

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan

Received 23 June 2005; received in revised form 28 July 2005; accepted 13 September 2005.

Rupture of hepatocellular carcinoma (HCC) is a fatal complication. Intraperitoneal metastasis after rupture of HCC is rare. We report a case of diffuse intraperitoneal metastases after rupture of HCC. A previously asymptomatic 32-year-old man was admitted because of massive ascites due to ruptured HCC. Poor liver reserve limited the therapeutic options. Transarterial chemoembolization was performed to stop tumor bleeding. Abdominal computed tomography demonstrated multiple large peritoneal metastases 3 months after the rupture episode. Echo-guided fine needle aspiration from the suprapubic area was performed. Cytology was positive for HCC. It is rare for HCC to develop intraperitoneal metastases in as short as 3 months.

Key Words:  hepatocellular carcinoma , peritoneal seeding , rupture

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PII: S0929-6646(09)60153-4

doi:10.1016/S0929-6646(09)60153-4

Journal of the Formosan Medical Association
Volume 105, Issue 7 , Pages 577-582, 2006

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