Journal of the Formosan Medical Association
Volume 106, Issue 6 , Pages 490-494, 2007

Reticular Dystrophy of the Retinal Pigment Epithelium

  • Muh-Shy Chen

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Muh-Shy Chen, Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, 7 Chung-Shan South Road, Taipei 100, Taiwan
  • ,
  • Ching-Chung Chang

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
  • ,
  • Tzu-Hsun Tsai

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
  • ,
  • I-More Fan

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
  • ,
  • Ping-Kang Hou

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan

Received 13 July 2006; received in revised form 5 October 2006; accepted 7 November 2006.

Article Outline

A laser flare-cell meter was used to examine blood-aqueous barrier function in a 57-year-old male patient who had typical reticular dystrophy of the retinal pigment epithelium with a bilateral hyperpigmented reticular pattern at the posterior pole in both eyes. Fluorescein angiography showed hypofluorescent reticular net resembling a fishing net with knots associated with a central diffuse hyperfluorescence. Dark adaptation test revealed that the final rod threshold was elevated. Laser photometry showed an increase in the aqueous flare intensity in both eyes, as compared to the results in normal subjects. Quantitative measurement of the aqueous flare intensity by a laser flare-cell meter might indicate abnormalities in the blood-aqueous barrier in patients with reticular dystrophy of the retinal pigment epithelium.

Key Words:  blood-aqueous barrier , reticular dystrophy of the retinal pigment epithelium

No full text is available. To read the body of this article, please view the PDF online.

 

Back to Article Outline

References 

  1. Sjögren H . Dystrophia reticularis laminae pigmentosae retinae . Acta Ophthalmol (Copenh) . 1950;28:279–295
  2. Chen MS , Tseng MC , Tsai CB , et al.   Quantitative assessment of aqueous flare intensity in retinitis pigmentosa . Trans Soc Ophthalmol Sin . 1993;32:60–62
  3. Sawa M , Tsurimaki Y , Tsuru T , et al.   New quantitative method to determine protein concentration and cell number in aqueous in vivo . Jpn J Ophthalmol . 1988;32:132–142
  4. Sawa M . Clinical application of laser flare-cell meter . Jpn J Ophthalmol . 1990;34:346–363
  5. Deutman AF , Rümke AML . Reticular dystrophy of the retinal pigment epithelium . Arch Ophthalmol . 1969;82:4–9
  6. Fishman GA , Woolf MB , Goldberg MF , et al.   Reticular tapeto-retinal dystrophy. A possible late stage of Sjögren's reticular dystrophy . Br J Ophthalmol . 1976;60:35–40
  7. Kingham JD , Fenzl RE , Willerson D , Aaberg TM . Reticular dystrophy of the retinal pigment epithelium. A clinical and electrophysiologic study of three generations . Arch Ophthalmol . 1978;96:1177–1184
  8. Marano F , Deutman AF , Pinckers AJLG , et al.   Reticular dystrophy of the retinal pigment epithelium and choroidal neovascularization . Acta Ophthalmol Scand . 1997;75:22–27
  9. Marmor MF , Byers B . Pattern dystrophy of the pigment epithelium . Am J Ophthalmol . 1977;84:32–44
  10. Hsieh RC , Fine BS , Lyons JB . Patterned dystrophies of the retinal pigment epithelium . Arch Ophthalmol . 1977;95:429–435
  11. Spalton DJ . Ocular fluorophotometry . Br J Ophthalmol . 1990;74:431–440
  12. Barsotti MF , Bartels SP , Freddo TF , et al.   The source of protein in the aqueous humor of the normal monkey eye . Invest Ophthalmol Vis Sci . 1992;33:581–591
  13. Sanders DR , Joondoph B , Hutchins R , et al.   Studies of the blood aqueous barrier after argon laser photocoagulation of the iris . Ophthalmology . 1983;90:169–174
  14. Yanagisawa S , Hayasaka S , Zhang XY , et al.   Effect of topical iganidipine on experimental elevation of aqueous flare induced by prostaglandin E2 and EP agonists in pigmented rabbits . Ophthalmic Res . 2002;34:195–199
  15. Abe T , Hayasaka Y , Zhang XY , et al.   Effects of intravenous administration of FR 122047 (a selective cyclooxygenase 1 inhibitor) and FR 188582 (a selective cyclooxygenase 2 inhibitor) on prostaglandin-E2-induced aqueous flare elevation in pigmented rabbits . Ophthalmic Res . 2004;36:321–326
  16. Butler JM , Unger WG , Grierson I . Recent experimental studies on the blood aqueous barrier: the anatomical basis of the response to injury . Eye . 1988;S212–S220

PII: S0929-6646(09)60299-0

doi:10.1016/S0929-6646(09)60299-0

Journal of the Formosan Medical Association
Volume 106, Issue 6 , Pages 490-494, 2007