Journal of the Formosan Medical Association
Volume 105, Issue 2 , Pages 105-117, 2006

Treatment of Type 2 Diabetes Mellitus in a Primary Care Setting in Taiwan: Comparison with Secondary/Tertiary Care

  • Tong-Yuan Tai

      Affiliations

    • Corresponding Author InformationCorrespondence to: Dr. Tong-Yuan Tai, Division of Gerontology Research, National Health Research Institutes, R4110, 4F, 161 Min-Chuan East Road, Section 6, Taipei 114, Taiwan, R.O.C.
  • Lee-Ming Chuang

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital, Taiwan, R.O.C.
  • ,
  • Shih-Tzer Tsai

      Affiliations

    • Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
  • ,
  • Bi-Yi Huang

      Affiliations

    • Chang-Gung Memorial Hospital, Keelung, Taiwan, R.O.C.
  • ,
  • The Diabcare (Taiwan) Study Group

Division of Gerontology Research, National Health Research Institutes

Received 7 December 2004; received in revised form 30 March 2005; accepted 5 July 2005.

Article Outline

Background

This study investigated the status of diabetes control and management in patients treated in a primary healthcare setting and compared the results with data previously obtained for secondary/tertiary care patients in Taiwan.

Methods

This study was conducted at 51 primary healthcare stations randomly selected island-wide in Taiwan in 2001. A total of 1302 type 2 diabetes patients who had been followed-up for more than 1 year were included. Blood was collected for centralized HbA1c assay. The remaining data and information were collected by review of medical records and patient interview.

Results

Compared with the results of a previous study on patients treated in a secondary/tertiary care setting, a significantly smaller percentage of primary care patients were receiving insulin therapy. Primary care patients also had a shorter duration of diabetes, a higher HbA1c level, better blood pressure control and a lower prevalence of complications. The proportion of patients achieving optimal control of glycemia and blood pressure was low. Patients aged < 65 years had a significantly shorter duration of diabetes, poorer diabetes control and better blood pressure control than elderly patients aged ≥ 65 years. Primary care patients aged ≥ 65 years had a significantly higher frequency of stroke than those aged < 65 years. The elderly group of secondary/tertiary care patients had a significantly higher frequency of coronary heart disease and stroke. Duration of diabetes and hypertension were the leading risk factors for complications in diabetes patients treated in both primary and secondary/tertiary care settings.

Conclusion

Diabetes control was poorer in primary care than in secondary/tertiary care patients, but control of blood pressure was better in primary care patients. The shorter duration of diabetes and better control of blood pressure in primary care patients and in patients aged < 65 years compared with their elderly counterparts might be related to a lower prevalence of complications.

Key Words:  blood pressure control , diabetes management , glycemic control , Taiwan , type 2 diabetes

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References 

  1. King H , Aubert RE , Herman WH . Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections . Diabetes Care . 1998;21:1414–1431
  2. Amos AF , McCarty DJ , Zimmet P . The rising global burden of diabetes and its complications: estimates and projections to the year 2010 . Diabet Med . 1997;14(Suppl 5):S1–85
  3. Tai T . Current status of diabetes in Taiwan . Diabetes Res Clin Pract . 2000;50(Suppl 2):S1–S2
  4. Wu L. One in Seven Senior Citizens in Taiwan Suffer from Diabetes. http://www.taipei.org/teco/cicc/news/english/e-03-15-02/e-03-15-02-19.htm [Date accessed: June 25, 2002]
  5. Lin T , Chou P , Lai MS , et al.   Direct costs-of-illness of patients with diabetes mellitus in Taiwan . Diabetes Res Clin Pract . 2001;54(Suppl 1):S43–S46
  6. Diabcare-Asia 2001  . Country Report on Outcome Data and Analyses . Singapore: Novo Nordisk Asia Pacific Pte Ltd; 29 January 2003;
  7. Chuang LM , Tsai ST , Huang BY , et al.   The status of diabetes control in Asia-a cross-sectional survey of 24317 patients with diabetes mellitus in 1998 . Diabet Med . 2001;19:978–985
  8. Morrish NJ , Stevens LK , Head J , et al.   A prospective study of mortality among middle-aged diabetic patients (the London Cohort of the WHO Multinational Study of Vascular Disease in Diabetics) II: Associated risk factors . Diabetologia . 1990;33:542–548
  9. Asia-Pacific Type 2 Diabetes Policy Group  . Type 2 Diabetes– Practical Target and Treatment . 3rd edition. Sydney, Australia: Health Communication Australia Ltd; 2002;
  10. American Diabetes Association  . Treatment of hypertension in adults with diabetes . Diabetes Care . 2002;25:199–201
  11. Kjeldsen SE , Farsang C , Sleigh P , et al.   World Health Organization; International Society of Hypertension. 1999 WHO/ ISH hypertension guidelines-highlights and ESH update . J Hypertens . 2001;19:2285–2288
  12. Soegonds S , Soewondo P , Semiardji G , et al.   The status of diabetes control in Indonesia: a national audit of patients with type 2 diabetes mellitus in the year 2001 . Maj Kedoht Indon . 2003;53:283–289
  13. Ohkubo Y , Kishikawa H , Araki E , et al.   Intensive insulin therapy prevents the progression of diabetic microvas-cular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study . Diabetes Res Clin Pract . 1995;28:103–117
  14. UK Prospective Diabetes Study (UKPDS) Group  . Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) . Lancet . 1998;352:837–853
  15. Wagner EH , Sandhu N , Newton KM , et al.   Effect of improved glycemic control on health care costs and utilization . JAMA . 2001;285:182–189
  16. Melkus GD , Maillet N , Novak J , et al.   Primary care cancer and diabetes complications screening of black women with type 2 diabetes . J Am Acad Nurse Pract . 2002;14:43–48
  17. Klein BE , Klein R , Wang Q , et al.   Older-onset diabetes and lens opacities. The Beaver Dam Eye Study . Ophthalmic Epidemiol . 1995;2:49–55
  18. McCarty CA , Mukesh BN , Fu CL , et al.   The epidemiology of cataract in Australia . Am J Ophthalmol . 1999;128:446–465
  19. Miglior S , Marighi PE , Musicco M , et al.   Risk factors for cortical, nuclear, posterior subcapsular and mixed cataract: a case-control study . Ophthalmic Epidemiol . 1994;1:93–105
  20. Hiller R , Sperduto RD , Ederer F . Epidemiologic associations with nuclear, cortical, and posterior subcapsular cataracts . Am J Epidemiol . 1986;124:916–925
  21. Leske MC , Chylack LT , Wu SY . The Lens Opacities Case-Control Study. Risk factors for cataract . Arch Ophthalmol . 1991;109:244–251
  22. Klein BEK , Klein R , Linton KLP . Prevalence of age-related lens opacities in a population: the Beaver Dam Eye Study . Ophthalmology . 1992;99:546–552
  23. Harding JJ , Egerton M , van Heyningen R , et al.   Diabetes, glaucoma, sex, and cataract: analysis of combined data from two case control studies . Br J Ophthalmol . 1993;77:2–6
  24. Giuffre G , Giammanco R , Di Pace F , et al.   Casteldaccia eye study: prevalence of cataract in the adult and elderly population of a Mediterranean town . Int Ophthalmol . 1994–95;18:363–371
  25. Delcourt C , Cristol JP , Tessier F , et al.   Risk factors for cortical, nuclear, and posterior subcapsular cataracts: the POLA study. Pathologies Oculaires Liées à l'Age . Am J Epidemiol . 2000;151:497–504
  26. Jahn CE , Janke M , Winowski H , et al.   Identification of metabolic risk factors for posterior subcapsular cataract . Ophthalmic Res . 1986;18:112–116
  27. Tsutsumi K , Inoue Y , Yoshida C . Acceleration of development of diabetic cataract by hyperlipidemia and low high-density lipoprotein in rats . Biol Pharm Bull . 1999;22:37–41
  28. Hiller R , Sperduto RD , Reed GF , et al.   Serum lipids and age-related lens opacities: a longitudinal investigation: the Framingham Studies . Ophthalmology . 2003;110:578–583
  29. Brown RD , Whisnant JP , Sicks JD , et al.   Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989 . Stroke . 1996;27:373–380
  30. Kannel WB , Wolf PA , Verter J , et al.   Epidemiologic assessment of the role of blood pressure in stroke. The Framingham Study . JAMA . 1970;214:301–310
  31. Menotti A , Jacobs DR , Blackburn H , et al.   Twenty-five-year prediction of stroke deaths in the Seven Countries Study: the role of blood pressure and its changes . Stroke . 1996;27:381–387
  32. Collins R , MacMahon S . Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease . Br Med Bull . 1994;50:272–298
  33. UK Prospective Diabetes Study Group  . Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 . BMJ . 1998;317:703–713
  34. Jungers P , Hannedouche T , Itakura Y , et al.   Progression rate to end-stage renal failure in non-diabetic kidney diseases: a multivariate analysis of determinant factors . Nephrol Dial Transplant . 1995;10:1353–1360
  35. Ishida K , Ishida H , Narita M , et al.   Factors affecting renal function in 119985 adults over three years . QJM . 2001;94:541–550
  36. Ravid M , Brosh D , Ravid-Safran D , et al.   Main risk factors for nephropathy in type 2 diabetes mellitus are plasma cholesterol levels, mean blood pressure, and hyperglycemia . Arch Intern Med . 1998;158:998–1004
  37. Kikuchi M , Matsumoto T , Ohashi Y . Risk factors for development of proteinuria in NIDDM analyzed by Poisson regression . J Diabet Complications . 1991;5:128–130
  38. Gall ML , Hougaard P , Borch-Johnsen K , et al.   Significant risk factors for development of microalbuminuria and diabetic nephropathy in patients with non-insulin-dependent diabetes . Ugeskr Laeger . 1998;160:4524–4527 [In Danish]
  39. Pijls LT , de Vries H , Kriegsman DM , et al.   Determinants of albuminuria in people with type 2 diabetes mellitus . Diabetes Res Clin Pract . 2001;52:133–143
  40. Basit A , Hydrie MZ , Hakeem R , et al.   Frequency of chronic complications of type II diabetes . J Coll Physicians Surg Pak . 2004;14:79–83
  41. Simon S , Stephenson S , Whyte K , et al.   Prevalence of chronic renal failure in the diabetic population at the University Hospital of the West Indies . West Indian Med J . 2004;53:85–88
  42. Barrera JA , Separza R . Renal functional reserve in patients with recently diagnosed type 2 diabetes mellitus with and without microalbuminuria . Nephron . 2001;87:223–230
  43. Ismail N , Becker B , Strzelczyk P , et al.   Renal disease and hypertension in non-insulin-dependent diabetes mellitus . Kidney Int . 1999;55:1–28
  44. Chen MS , Kao CS , Chang CJ , et al.   Prevalence and risk factors of diabetic retinopathy among non-insulin-dependent diabetes subjects . Am J Ophthalmol . 1992;114:723–730

PII: S0929-6646(09)60331-4

doi:10.1016/S0929-6646(09)60331-4

Journal of the Formosan Medical Association
Volume 105, Issue 2 , Pages 105-117, 2006