Journal of the Formosan Medical Association
Volume 106, Issue 2, Supplement , Pages S55-S59 , 2007

Occult Subcutaneous Panniculitis-like T-cell Lymphoma with Initial Presentations of Cellulitis-like Skin Lesion and Fulminant Hemophagocytosis

  • Huey-En Tzeng

      Affiliations

    • Division of Hematology/Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    • ,
  • Chieh-Lin Teng

      Affiliations

    • Division of Hematology/Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    • ,
  • Youngsen Yang

      Affiliations

    • Division of Hematology/Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Youngsen Yang, Division of Hematology/Oncology, Taichung Veterans General Hospital, 160, Section 3, Taichung-Kang Road, Taichung, Taiwan
    • ,
  • Ji-Hsiung Young

      Affiliations

    • Division of Hematology/Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    • ,
  • Guan Chou

      Affiliations

    • Department of Pathology, Taichung Veterans General Hospital, Taichung, Taiwan

Received 18 November 2005 ,Revised 3 January 2006 ,Accepted 4 April 2006.

References 

  1. Henter JI , Elinder G , Ost A . Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society . Semin Oncol . 1991;18:29–33
  2. Henter JI , Arico M , Elinder G , et al.   Familial hemophagocytic lymphohistiocytosis. Primary hemophagocytic lymphohistiocytosis . Hematol Oncol Clin North Am . 1998;12:417–433
  3. Takahashi N , Chubachi A , Kume M , et al.   A clinical analysis of 52 adult patients with hemophagocytic syndrome: the prognostic significance of the underlying diseases . Int J Hematol . 2001;74:209–213
  4. McKenna RW , Risdall RJ , Brunning RD . Virus associated hemophagocytic syndrome . Hum Pathol . 1981;12:395–398
  5. Larroche C , Mouthon L . Pathogenesis of hemophagocytic syndrome (HPS) . Autoimmun Rev . 2004;3:69–75
  6. Takada H , Nomura A , Ohga S , et al.   Interleukin-18 in hemophagocytic lymphohistiocytosis . Leuk Lymphoma . 2001;42:21–28
  7. Osugi Y , Hara J , Tagawa S , et al.   Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis . Blood . 1997;89:4100–4103
  8. Fisman DN . Hemophagocytic syndromes and infection . Emerg Infect Dis . 2000;6:601–608
  9. Chang CS , Wang CH , Su IJ , et al.   Hematophagic histiocytosis: a clinicopathologic analysis of 23 cases with special reference to the association with peripheral T-cell lymphoma . J Formos Med Assoc . 1994;93:421–428
  10. Florena AM , Iannitto E , Quintini G , et al.   Bone marrow biopsy in hemophagocytic syndrome . Virchows Arch . 2002;441:335–344
  11. Weenig RH , Ng CS , Perniciaro C . Subcutaneous panniculitis-like T-cell lymphoma: an elusive case presenting as lipomembranous panniculitis and a review of 72 cases in the literature . Am J Dermatopathol . 2001;23:206–215
  12. Goldschmidt N , Gural A , Kornberg A , et al.   Prolonged fever of unknown origin and hemophagocytosis evolving into acute lymphoblastic leukemia . Am J Hematol . 2004;76:364–367
  13. Go RS , Wester SM . Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma: a systematic analysis of 156 patients reported in the literature . Cancer . 2004;101:1404–1413
  14. Burg G , Dummer R , Wilhelm M , et al.   A subcutaneous delta-positive T-cell lymphoma that produces interferon gamma . N Engl J Med . 1991;325:1078–1081
  15. Papenfuss JS , Aoun P , Bierman PJ , et al.   Subcutaneous panniculitis-like T-cell lymphoma: presentation of 2 cases and observations . Clin Lymphoma . 2002;3:175–180
  16. Ghobrial IM , Weenig RH , Pittlekow MR , et al.   Clinical outcome of patients with subcutaneous panniculitis-like T-cell lymphoma . Leuk Lymphoma . 2005;46:703–708

PII: S0929-6646(09)60354-5

doi: 10.1016/S0929-6646(09)60354-5

Journal of the Formosan Medical Association
Volume 106, Issue 2, Supplement , Pages S55-S59 , 2007

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