Journal of the Formosan Medical Association
Volume 108, Issue 7 , Pages 526-532 , July 2009

Novel Swine-origin Influenza Virus A (H1N1): The First Pandemic of the 21st Century

  • Luan-Yin Chang

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    • Luan-Yin Chang and Shin-Ru Shih contributed equally to this work.
  • ,
  • Shin-Ru Shih

      Affiliations

    • Research Center for Emerging Viral Infections, National Taiwan University, Taipei, Taiwan
    • Department of Medical Biotechnology and Laboratory Science, National Taiwan University, Taipei, Taiwan
    • Clinical Virology Laboratory, Chang-Gung Memorial Hospital, National Taiwan University, Taipei, Taiwan
    • Luan-Yin Chang and Shin-Ru Shih contributed equally to this work.
  • ,
  • Pei-Lan Shao

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
  • ,
  • Daniel Tsung-Ning Huang

      Affiliations

    • Department of Pediatrics, Mackay Memorial Hospital, National Taiwan University, Taipei, Taiwan
  • ,
  • Li-Min Huang

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    • Graduate Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Li-Min Huang, Department of Pediatrics, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei 100, Taiwan

Received 5 June 2009 ,Revised 13 June 2009 ,Accepted 14 June 2009.

References 

  1. World Health Organization  . Influenza A (H1N1)—Update 40 . Available at http://www.who.int/csr/don/2009_06_12/en/index.html [Date accessed: June 14, 2009]
  2. Miller MA , Viboud C , Balinska M , et al.   The signature features of influenza pandemics—implications for policy . N Engl J Med . 2009 May 7; [Epub ahead of print]
  3. Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team  . Emergence of a novel swine-origin influenza A (H1N1) virus in humans . N Engl J Med . 2009;360:2605–2615
  4. Katz J , Hancock K , Veguilla V , et al.   Serum cross-reactive antibody response to a novel influenza A (H1N1) virus after vaccination with seasonal influenza vaccine . MMWR Morb Mortal Wkly Rep . 2009;58:521–524
  5. Fraser C , Donnelly CA , Cauchemez S , et al.   Pandemic potential of a strain of influenza A (H1N1): early findings . Science . 2009 May 14; [Epub ahead of print]
  6. Shope RE . The etiology of swine influenza . Science . 1931;73:214–215
  7. Smith W , Andrewes CH , Laidlaw PP . A virus obtained from influenza patients . Lancet . 1993;2:66–68
  8. Reid AH , Taubenberger JK . The origin of the 1918 pandemic influenza virus: a continuing enigma . J Gen Virol . 2003;84:2285–2292
  9. Tumpey TM , Garcia-Sastre A , Taubenberger JK , et al.   Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus . Proc Natl Acad Sci USA . 2004;101:3166–3171
  10. Sheerar MG , Easterday BC , Hinshaw VS . Antigenic conservation of H1N1 swine influenza viruses . J Gen Virol . 1989;70:3297–3303
  11. Vincent AL , Lager KM , Ma W , et al.   Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United States . Vet Microbiol . 2006;118:212–222
  12. Karasin AI , Schutten MM , Cooper LA , et al.   Genetic characterization of H3N2 influenza viruses isolated from pigs in North America, 1977–1999: evidence for wholly human and reassortant virus genotypes . Virus Res . 2000;68:71–85
  13. Webby RJ , Swenson SL , Krauss SL , et al.   Evolution of swine H3N2 influenza viruses in the United States . J Virol . 2000;74:8243–8251
  14. Zhou NN , Senne DA , Landgraf JS , et al.   Genetic reassortment of avian, swine, and human influenza A viruses in American pigs . J Virol . 1999;73:8851–8856
  15. Garten RJ , Davis CT , Russell CA , et al.   Antigenic and genetic characteristics of swine-origin 2009 A (H1N1) influenza viruses circulating in humans . Science . 2009 May 22; [Epub ahead of print]
  16. Shinde V , Bridges CB , Uyeki TM , et al.   Triple-reassortant swine influenza A (H1) in humans in the United States, 2005–2009 . N Engl J Med . 2009 May 22; [Epub ahead of print]
  17. Subbarao EK , London W , Murphy BR . A single amino acid in the PB2 gene of influenza A virus is a determinant of host range . J Virol . 1993;67:1761–1764
  18. Steel J , Lowen AC , Mubareka S , et al.   Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N . PLoS Pathog . 2009;5: e1000252.
  19. Fouchier RA , Schneeberger PM , Rozendaal FW , et al.   Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome . Proc Natl Acad Sci USA . 2004;101:1356–1361
  20. Zamarin D , Ortigoza MB , Palese P . Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice . J Virol . 2006;80:7976–7983
  21. Chen GW , Yang CC , Tsao KC , et al.   Influenza A virus PB1-F2 gene in recent Taiwanese isolates . Emerg Infect Dis . 2004;10:630–636
  22. Hale BG , Randall RE , Ortin J , et al.   The multifunctional NS1 protein of influenza A viruses . J Gen Virol . 2008;89:2359–2376
  23. Chen GW , Chang SC , Mok CK , et al.   Genomic signatures of human versus avian influenza A viruses . Emerg Infect Dis . 2006;12:1353–1360
  24. Treanor JJ , Wilkinson BE , Masseoud F , et al.   Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans . Vaccine . 2001;19:1732–1737
  25. Schonberger LB , Bregman DJ , Sullivan-Bolyai JZ , et al.   Guillain-Barre syndrome following vaccination in the National Influenza Immunization Program, United States, 1976–1977 . Am J Epidemiol . 1979;110:105–123
  26. Nachamkin I , Shadomy SV , Moran AP , et al.   Anti-ganglioside antibody induction by swine (A/NJ/1976/H1N1) and other influenza vaccines: insights into vaccine-associated Guillain-Barré syndrome . J Infect Dis . 2008;198:226–233

PII: S0929-6646(09)60369-7

doi: 10.1016/S0929-6646(09)60369-7

Journal of the Formosan Medical Association
Volume 108, Issue 7 , Pages 526-532 , July 2009