Journal of the Formosan Medical Association
Volume 108, Issue 7 , Pages 587-591 , July 2009

Construction of Balanced Translocation t(1;11)(q42.1;q14.3) Probe and Screening Application in Genomic Samples in Taiwan

  • Yu-Li Liu

      Affiliations

    • Division of Mental Health and Substance Abuse Research, National Health Research Institutes, Miaoli, Taiwan
    • ,
  • Chih-Min Liu

      Affiliations

    • Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Hwei-Fang Tien

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Hai-Gwo Hwu

      Affiliations

    • Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Hai-Gwo Hwu, Department of Psychiatry, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei 100, Taiwan

Received 9 October 2008 ,Revised 20 October 2008 ,Accepted 20 November 2008.

References 

  1. Blackwood DH , Fordyce A , Walker MT , et al.   Schizophrenia and affective disorders—cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family . Am J Hum Genet . 2001;69:428–433
  2. Millar JK , Christie S , Anderson S , et al.   Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia . Mol Psychiatry . 2001;6:173–178
  3. St Clair D , Blackwood D , Muir W , et al.   Association within a family of a balanced autosomal translocation with major mental illness . Lancet . 1990;336:13–16
  4. Millar JK , Wilson-Annan JC , Anderson S , et al.   Disruption of two novel genes by a translocation co-segregating with schizophrenia . Hum Mol Genet . 2000;9:1415–1423
  5. Parvari R , Hershkovitz E , Kanis A , et al.   Homozygosity and linkage-disequilibrium mapping of the syndrome of congenital hypoparathyroidism, growth and mental retardation, and dysmorphism to a 1-cM interval on chromosome 1q42-43 . Am J Hum Genet . 1998;63:163–169
  6. Garver DL , Holcomb J , Mapua FM , et al.   Schizophrenia spectrum disorders: an autosomal-wide scan in multiplex pedigrees . Schizophr Res . 2001;52:145–160
  7. Hovatta I , Varilo T , Suvisaari J , et al.   A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci . Am J Hum Genet . 1999;65:1114–1124
  8. Ekelund J , Hovatta I , Parker A , et al.   Chromosome 1 loci in Finnish schizophrenia families . Hum Mol Genet . 2001;10:1611–1617
  9. Hwu HG , Liu CM , Fann CS , et al.   Linkage of schizophrenia with chromosome 1q loci in Taiwanese families . Mol Psychiatry . 2003;8:445–452
  10. Liu YL , Fann CS , Liu CM , et al.   A single nucleotide polymorphism fine mapping study of chromosome 1q42.1 reveals the vulnerability genes for schizophrenia, GNPAT and DISC1: association with impairment of sustained attention . Biol Psychiatry . 2006;60:554–562
  11. Chen QY , Chen Q , Feng GY , et al.   Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population . J Psychiatr Res . 2007;41:428–434
  12. Van Dyke DL , Weiss L , Roberson JR , et al.   The frequency and mutation rate of balanced autosomal rearrangements in man estimated from prenatal genetic studies for advanced maternal age . Am J Hum Genet . 1983;35:301–308
  13. Boue A , Gallano P . A collaborative study of the segregation of inherited chromosome structural rearrangements in 1356 prenatal diagnoses . Prenat Diagn . 1984;4:45–67
  14. Hwu HG . In: Psychiatric Diagnostic Assessment. Manual of Psychiatric Diagnosis . Taipei: College of Medicine, National Taiwan University; 1999;p. 7–42
  15. Spitz F , Montavon T , Monso-Hinard C , et al.   A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects . Genomics . 2002;79:493–498
  16. Holinski-Feder E , Reyniers E , Uhrig S , et al.   Familial mental retardation syndrome ATR-16 due to an inherited cryptic subtelomeric translocation, t(3;16)(q29;p13.3) . Am J Hum Genet . 2000;66:16–25
  17. de Lomas JG , Sunzeri FJ , Busch MP . False-negative results by polymerase chain reaction due to contamination by glove powder . Transfusion . 1992;32:83–85
  18. Burkardt HJ . Standardization and quality control of PCR analyses . Clin Chem Lab Med . 2000;38:87–91
  19. Johannesson T , Ehlers S , Wahlstrom J . Complex chromosome rearrangement involving chromosomes 1, 4 and 16 revealed by fluorescence in situ hybridization . Clin Genet . 1997;51:281–285
  20. Novelli A , Sabani M , Caiola A , et al.   Diagnosis of DiGeorge and Williams syndromes using FISH analysis of peripheral blood smears . Mol Cell Probes . 1999;13:303–307

PII: S0929-6646(09)60377-6

doi: 10.1016/S0929-6646(09)60377-6

Journal of the Formosan Medical Association
Volume 108, Issue 7 , Pages 587-591 , July 2009

Article Tools