Journal of the Formosan Medical Association
Volume 108, Issue 9 , Pages 739-745, September 2009

Combined Pancreatic Endocrine Tumor and Serous Cystadenoma

  • Min-Shu Hsieh

      Affiliations

    • Department of Pathology, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin
    • ,
  • Kao-Lang Liu

      Affiliations

    • Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
    • ,
  • Yu-Wen Tien

      Affiliations

    • Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan
    • ,
  • Chia-Tung Shun

      Affiliations

    • Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Chia-Tung Shun, Department of Pathology, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan

Received 22 September 2008; received in revised form 26 November 2008; accepted 6 February 2009.

Article Outline

Pancreatic serous cystadenomas account for 1–2% of all exocrine pancreatic tumors, and endocrine tumors account for 1–2% of all pancreatic neoplasms. The combination of pancreatic serous cystadenoma and endocrine tumor is even rarer. Here, we report two cases of combined pancreatic serous adenoma and endocrine tumor. One was a 64-year-old woman with serous cystadenoma and pancreatic endocrine tumor. The other case was a 28-year-old woman with von Hippel–Lindau disease with combined pancreatic serous oligocystic adenoma and well-differentiated malignant endocrine carcinoma. Reviewing the literature, we found 15 similar cases that showed two different age distributions and clinical presentations. Careful examination of benign serous cystadenoma should be kept in mind during clinical practice, to rule out the possibility of combined malignant endocrine tumor. In addition, von Hippel–Lindau disease should also be suspected when a young adult presents with combination of pancreatic serous cystadenoma and endocrine tumor.

Key Words:  cystadenoma , pancreatic neoplasms , serous

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References 

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PII: S0929-6646(09)60399-5

doi:10.1016/S0929-6646(09)60399-5

Journal of the Formosan Medical Association
Volume 108, Issue 9 , Pages 739-745, September 2009

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