Sarcoidosis is an inflammatory disease characterized by non-caseating granulomas in the absence of other autoimmune processes, infectious diseases, or foreign agents. The etiology of sarcoidosis is not completely understood. Several organ systems can be affected, of which the most frequently involved include the lungs and lymph nodes. Intra-abdominal sarcoidosis is less common, but can be found in the absence of pulmonary or lymphatic disease. Intra-abdominal sarcoidosis is most often asymptomatic. However, long-standing unrecognized disease can result in life-threatening complications. The identification, monitoring and prevention of these complications will be discussed, with emphasis on both clinical and histological presentations of intra-abdominal sarcoidosis.
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aDepartment of Medicine, University of Connecticut Health Center, Farmington, USA
bDepartment of Anatomical Pathology, University of Connecticut Health Center, Farmington, USA
Correspondence to: Dr George Y. Wu, Department of Medicine, Division of Gastroenterology Hepatology, University of Connecticut Health Center, Rm. AM-044, 263 Farmington Ave, Farmington, CT 06030, USA